H2a2a, The most likely estimate is 5724 BCE, rounded to 5700 BCE

H2a2a, H1 & H3 Haplogroup H1 is by far the most common subclade in Europe, representing approximately than half of the H lineages in Western Europe. Jan 23, 2007 · UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information. By tracking these changes, we constructed a family tree of humankind where all female lineages trace back to a single common ancestor who lived hundreds of thousands of years ago. That means that This date is an estimate based on genetic information only. Oct 20, 2012 · However, someone who falls into haplogroup H2a2a won’t show any of these mutations on their list of mutations on their personal page that differs from the CRS, because the CRS is defined as “normal” and everything else is a mutation. However, a specimen has been found in South Italy from 28,000 years ago, in Paglicci Cave. Mitochondrial haplogroup H is today predominantly found in Europe, and is believed to have evolved before the Last Glacial Nov 10, 2006 · Abstract. The Cambridge Reference Sequence (CRS), the human mitochondrial sequence to which all other sequences are compared, belongs to haplogroup H2a2a. This date is an estimate based on genetic information only. The clade was believed to have originated in West Asia, near present-day Syria, [1] around 20,000 to 25,000 years ago. Jan 15, 2026 · ( Q6FI13-H2A2A_HUMAN ) Crotonylation (Kcr) is specifically present in male germ cells and marks testis-specific genes in post-meiotic cells, including X-linked genes that escape sex chromosome inactivation in haploid cells. These results, shown above, with the exception of two mutations in the HVR2 region, are equivalent to the Cambridge Reference Sequence. Apr 2, 2015 · Tree This phylogenetic tree of haplogroup H subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation [PMID 18853457] and subsequent published research. , 2020). This estimate will likely change in the future as more people test and we improve the method. The European lineage of Kalash population is reported by (Rahman et al. The Scientific Details section contains more information. We would like to show you a description here but the site won’t allow us. For people who have tested and are assigned the maternal haplogroup H2a2 or who are believed to have had that maternal haplogroup based on descendants tested. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Defining Mutations (to be added) Origin In his popular book The Seven Daughters of Eve, Bryan Sykes named the originator of this mtDNA haplogroup Helena. Haplogroup H is a human mitochondrial DNA (mtDNA) haplogroup. The most likely estimate is 5724 BCE, rounded to 5700 BCE. Oct 23, 2021 · All detected variants are represented for more explication and construction of the phylogenetic tree compared with the rCRS haplogroup (H2a2a) for establishment of the haplogroup affiliation and motifs, following the nomenclature of mtDNA tree Build 17 (Figure 2). With a 95% probability, the ancestor H2a2a was born between the years 6270 and 5197 BCE. The haplotype frequency also suggest the European lineage of Kalash population. Your Haplogroup Story: H2a2a The mitochondria are passed from mother to child remaining mostly unaltered across generations, except for small traceable changes in DNA. Distribution (to be added) Subclades of H H (mtDNA) H1 (mtDNA) H1c (mtDNA) H1c1 . More than a third of the European pool of human mitochondrial DNA (mtDNA) is fragmented into a number of subclades of haplogroup (hg) H, the most Jun 1, 2021 · The haplotype H2a2a is the prevalent haplotype in European population.


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